| Date / Time | Away Team | Home Team | Arena | |
| 04/28/2012 7:00 PM EST | Rattlers | @ | Cannons | Harvard Stadium |
| 04/28/2012 7:00 PM EST | Outlaws | @ | Hounds | American Legion Memorial Stadium |
| 04/28/2012 7:00 PM EST | Bayhawks | @ | Lizards | James M. Shuart Stadium |
| 05/05/2012 7:00 PM EST | Hounds | @ | Cannons | Harvard Stadium |
| 05/05/2012 7:00 PM EST | Machine | @ | Bayhawks | Navy-Marine Corps Memorial Stadium |
| 05/05/2012 9:00 PM EST | Nationals | @ | Outlaws | Sports Authority Field at Mile High |
| 05/12/2012 7:00 PM EST | Nationals | @ | Cannons | Harvard Stadium |
| 05/12/2012 7:00 PM EST | Machine | @ | Hounds | American Legion Memorial Stadium |
| 05/12/2012 7:00 PM EST | Rattlers | @ | Bayhawks | Navy-Marine Corps Memorial Stadium |
| 05/12/2012 9:00 PM EST | Lizards | @ | Outlaws | Sports Authority Field at Mile High |
| 05/18/2012 11:00 AM EST | Bayhawks | @ | Nationals | Ron Joyce Stadium |
| 05/19/2012 7:00 PM EST | Lizards | @ | Hounds | American Legion Memorial Stadium |
| 05/19/2012 8:00 PM EST | Rattlers | @ | Machine | Selby Stadium |
| 05/19/2012 9:00 PM EST | Cannons | @ | Outlaws | Sports Authority Field at Mile High |
| 06/01/2012 7:00 PM EST | Machine | @ | Lizards | James M. Shuart Stadium |
| 06/01/2012 7:00 PM EST | Cannons | @ | Rattlers | Sahlen's Stadium |
| 06/02/2012 7:00 PM EST | Nationals | @ | Hounds | American Legion Memorial Stadium |
| 06/02/2012 9:00 PM EST | Bayhawks | @ | Outlaws | Sports Authority Field at Mile High |
| 06/09/2012 7:00 PM EST | Lizards | @ | Cannons | Harvard Stadium |
| 06/09/2012 7:00 PM EST | Hounds | @ | Bayhawks | Navy-Marine Corps Memorial Stadium |
| 06/09/2012 7:00 PM EST | Outlaws | @ | Machine | Selby Stadium |
| 06/09/2012 7:30 PM EST | Rattlers | @ | Nationals | Ron Joyce Stadium |
| 06/16/2012 7:00 PM EST | Cannons | @ | Hounds | American Legion Memorial Stadium |
| 06/16/2012 7:00 PM EST | Nationals | @ | Bayhawks | Navy-Marine Corps Memorial Stadium |
| 06/16/2012 7:00 PM EST | Lizards | @ | Machine | Selby Stadium |
| 06/16/2012 9:00 PM EST | Rattlers | @ | Outlaws | Sports Authority Field at Mile High |
| 06/23/2012 7:00 PM EST | Cannons | @ | Bayhawks | Navy-Marine Corps Memorial Stadium |
| 06/23/2012 7:00 PM EST | Hounds | @ | Machine | Selby Stadium |
| 06/23/2012 7:00 PM EST | Outlaws | @ | Lizards | James M. Shuart Stadium |
| 06/23/2012 7:00 PM EST | Nationals | @ | Rattlers | Sahlen's Stadium |
| 06/30/2012 7:30 PM EST | All-Star Game | |||
| 07/04/2012 9:00 PM EST | Machine | @ | Outlaws | Sports Authority Field at Mile High |
| 07/06/2012 7:00 PM EST | Lizards | @ | Rattlers | Sahlen's Stadium |
| 07/07/2012 7:00 PM EST | Bayhawks | @ | Hounds | American Legion Memorial Stadium |
| 07/07/2012 7:30 PM EST | Rattlers | @ | Lizards | James M. Shuart Stadium |
| 07/07/2012 7:30 PM EST | Cannons | @ | Nationals | Ron Joyce Stadium |
| 07/13/2012 7:30 PM EST | Machine | @ | Nationals | Ron Joyce Stadium |
| 07/14/2012 7:00 PM EST | Nationals | @ | Machine | Selby Stadium |
| 07/14/2012 7:00 PM EST | Cannons | @ | Lizards | James M. Shuart Stadium |
| 07/14/2012 7:00 PM EST | Hounds | @ | Outlaws | Sports Authority Field at Mile High |
| 07/14/2012 7:00 PM EST | Bayhawks | @ | Rattlers | Sahlen's Stadium |
| 07/19/2012 7:00 PM EST | Outlaws | @ | Cannons | Harvard Stadium |
| 07/20/2012 7:00 PM EST | Hounds | @ | Rattlers | Sahlen's Stadium |
| 07/21/2012 7:00 PM EST | Nationals | @ | Lizards | |
| 07/21/2012 8:00 PM EST | Bayhawks | @ | Machine | Selby Stadium |
| 07/28/2012 2:00 PM EST | Bayhawks | @ | Cannons | Harvard Stadium |
| 07/28/2012 7:00 PM EST | Hounds | @ | Lizards | James M. Shuart Stadium |
| 07/28/2012 7:00 PM EST | Machine | @ | Rattlers | Sahlen's Stadium |
| 07/28/2012 7:30 PM EST | Outlaws | @ | Nationals | Ron Joyce Stadium |
| 08/04/2012 7:00 PM EST | Machine | @ | Cannons | Harvard Stadium |
| 08/04/2012 7:00 PM EST | Lizards | @ | Bayhawks | Navy-Marine Corps Memorial Stadium |
| 08/04/2012 7:00 PM EST | Outlaws | @ | Rattlers | Sahlen's Stadium |
| 08/04/2012 7:30 PM EST | Hounds | @ | Nationals | Ron Joyce Stadium |
| 08/11/2012 7:00 PM EST | Cannons | @ | Machine | Selby Stadium |
| 08/11/2012 7:00 PM EST | Rattlers | @ | Hounds | American Legion Memorial Stadium |
| 08/11/2012 7:00 PM EST | Outlaws | @ | Bayhawks | Navy-Marine Corps Memorial Stadium |
| 08/11/2012 7:30 PM EST | Lizards | @ | Nationals | Ron Joyce Stadium |
| 08/25/2012 1:00 PM EST | Playoff Game | |||
| 08/25/2012 4:00 PM EST | Playoff Game | |||
| 08/26/2012 3:00 PM EST | Championship Game |